• Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer 

      Mazloumi Gavgani, Fatemeh; Arnesen, Victoria Smith; Jacobsen, Rhian Gaenor; Krakstad, Camilla; Høivik, Erling Andre; Lewis, Aurelia Eva (Peer reviewed; Journal article, 2018-12-07)
      The phosphoinositide 3-kinase (PI3K) signalling pathway is highly dysregulated in cancer, leading to elevated PI3K signalling and altered cellular processes that contribute to tumour development. The pathway is normally ...
    • Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with high 47S rRNA levels in cancer cells 

      Mazloumi Gavgani, Fatemeh; Karlsson, Thomas; Tangen, Ingvild Løberg; Papdine Morovicz, Andrea; Arnesen, Victoria Smith; Turcu, Diana Cornelia; Ninzima, Sandra; Spang, Katharina Maria; Krakstad, Camilla; Guillermet-Guibert, Julie; Lewis, Aurelia Eva (Journal article; Peer reviewed, 2021)
      The class I phosphoinositide 3-kinase (PI3K) catalytic subunits p110α and p110β are ubiquitously expressed but differently targeted in tumours. In cancer, PIK3CB (encoding p110β) is seldom mutated compared with PIK3CA ...